>TTK_HUMAN/509-775
YSILKQIGSGGSSKV..FQVLNEKKQI.........YAIKYVNLEEADNQTLDSYRN...
................EIAYLNKLQQ..HSDKI..IRLYDYEIT................
..DQYIY..MVMECGNI......DLN..SWLK................KKKSI...DPWE
RKSYWKNMLEAVHTIHQ.H..........GIVHSDLKPANFLIV..DGML..........
.........KLIDFGIANQMQ...............PDTTSV.VKDSQVGTVNYMPP...
.EA....IKDMSSS....RENGKSKSKISPKSDVWSLGCILYYMTY.....GK......T
PFQ.QI.......INQISKLHAIIDPNHEIEFPDIPE.......................
..................KDLQDVLKCCLKRDPKQRIS.....IPELLAHPYV
>CLK1_MOUSE/160-476
YEIVDTLGEGAFGKVVECIDHKVGGRR.........VAVKIVKNVDRYCEAAQS......
................EIQVLEHLNTTDPHSTFRCVQMLEWFEH................
..RGHIC..IVFELL........GLSTYDFIK.................ENSFLPFRMDH
IRKMAYQICKSVNFLHS.N..........KLTHTDLKPENILFV.KSDYTEAYNPKMKRD
ERTIVNPDIKVVDFGSA....................TYDDE.HHSTLVSTRHYRAP...
.EV....IL...............ALGWSQPCDVWSIGCILIEYYL.....GF......T
VFP.TH.....DSREHLAMMERILGPLPKHMIQKTRKRRYFHHDRLDWDEHSSAGRY..V
SRRCKPLKEFMLSQDAEHEFLFDLVGKILEYDPAKRIT.....LKEALKHPFF
>FUSED_DROME/4-254
YAVSSLVGQGSFGCV..YKATRKDDSK........VVAIKVISKRGRATKELKNLRR...
................ECDIQARL.K...HPHV..IEMIESFES................
..KTDLF..VVTEFALM......DLH..RYLS................YNGAM...GEEP
ARRVTGHLVSALYYLHS.N..........RILHRDLKPQNVLLD.KNMHA..........
.........KLCDFGLARNM.................TLGTH.VLTSIKGTPLYMAP...
.EL....LA...............EQPYDHHADMWSLGCIAYESMA.....GQ......P
PFC.AS........SILHLVKMIKHEDVKWPSTLT.........................
..................SECRSFLQGLLEKDPGLRIS.....WTQLLCHPFV
>AKT_MLVAT/171-429
FEYLKLLGKGTFGKV..ILVKEKATGR........YYAMKILKKEVIVAKDEVAHTLT..
................ENRVLQNS.R...HPFL..TALKYSFQT................
..HDRLC..FVMEYANGG.....ELF..FHLS................RERVF...SEDR
ARFYGAEIVSALDYLHSEK..........NVVYRDLKLENLMLD.KDGHI..........
.........KITDFGLCKEG.................IKDGA.TMKTFCGTPEYLAP...
.EV....LE...............DNDYGRAVDWWGLGVVMYEMMC.....GR......L
PFY.NQ........DHEKLFELILMEEIRFPRTLG.........................
..................PEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFF
>KIN82_YEAST/324-602
FEKIRLLGQGDVGKV..YLMRERDTNQ........IFALKVLNKHEMIKRKKIKRVLT..
................EQEILATS.D...HPFI..VTLYHSFQT................
..KDYLY..LCMEYCMGG.....EFF..RALQ..............TRKSKCI...AEED
AKFYASEVVAALEYLHL.L..........GFIYRDLKPENILLH.QSGHV..........
.........MLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAP...
.EV....IR...............GNGHTAAVDWWTLGILIYEMLF.....GC......T
PFK.GD........NSNETFSNILTKDVKFPHDKEVS.......................
..................KNCKDLIKKLLNKNEAKRLGSK.SGAADIKRHPFF
>PKD1_DICDI/36-291
FNFYGSLGSGSFGTA..KLCRHRGSGL........FFCSKTLRRETIVHEKHKEHVNN..
................EINIMLNI.S...HPYI..VKTYSTFNT................
..PTKIH..FIMEYAGKK.....DLF..HHLR................ANKCF...TEQT
TKLIVAEIVLAIEYLHA.E..........NIIYRDLKPENILID.EKGHI..........
.........KLTDFGFSKK..................TVGGK.NTSSVCGTFDYMAP...
.EI....LN..............SSNGHGKPVDWWALGVVVYELVT.....GK......L
PFS.NSKESLLNRKADFQLIFQNSYLS.................................
..................DEIKDFIFQLLSVDPSKRLGT..FDSCSIRNHKWF
>KGP1_DROME/457-717
LEVVSTLGIGGFGRVELVKAHHQDRVD........IFALKCLKKRHIVDTKQEEHIFS..
................ERHIMLSS.R...SPFI..CRLYRTFRD................
..EKYVY..MLLEACMGG.....EIW..TMLR................DRGSF...EDNA
AQFIIGCVLQAFEYLHA.R..........GIIYRDLKPENLMLD.ERGYV..........
.........KIVDFGFAKQ..................IGTSS.KTWTFCGTPEYVAP...
.EI....IL...............NKGHDRAVDYWALGILIHELLN.....GT......P
PFS.AP........DPMQTYNLILKGIDMIAFPKHIS.......................
..................RWAVQLIKRLCRDVPSERLGYQTGGIQDIKKHKWF
>ARBK1_BOVIN/191-453
FSVHRIIGRGGFGEV..YGCRKADTGK........MYAMKCLDKKRIKMKQGETLAL...
................NERIMLSLVSTGDCPFI..VCMSYAFHT................
..PDKLS..FILDLMNGG.....DLH..YHLS................QHGVF...SEAD
MRFYAAEIILGLEHMHN.R..........FVVYRDLKPANILLD.EHGHV..........
.........RISDLGLAC...................DFSKK.KPHASVGTHGYMAP...
.EV....LQ..............KGVAYDSSADWFSLGCMLFKLLR.....GH......S
PFR.QH.....KTKDKHEIDRMTLTMAVELPDSFS.........................
..................PELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFF
>CHK1_SCHPO/10-272
YHIGREIGTGAFASV..RLCYDDNAKI.........YAVKFVNKKHATSCMNAGVWARR.
.............MASEIQLHKLCNG...HKNI..IHFYNTAEN................
..PQWRW..VVLEFAQGG.....DLF..DKIE................PDVGI...DEDV
AQFYFAQLMEGISFMHS.K..........GVAHRDLKPENILLD.YNGNL..........
.........KISDFGFASLFS...............YKGKSR.LLNSPVGSPPYAAP...
.EI....................TQQYDGSKVDVWSCGIILFALLL.....GN......T
PWD.EA.....ISNTGDYLLYKKQCERPSYHPWNLLS.......................
..................PGAYSIITGMLRSDPFKRYS.....VKHVVQHPWL
>CDC5_YEAST/82-337
YHRGHFLGEGGFARC..FQIKDDSGEI.........FAAKTVAKASIKSEKTRKKLLS..
................EIQIHKSM.S...HPNI..VQFIDCFED................
..DSNVY..ILLEICPNG.....SLM..ELLK................RRKVL...TEPE
VRFFTTQICGAIKYMHS.R..........RVIHRDLKLGNIFFD.SNYNL..........
.........KIGDFGLAAVL.................ANESE.RKYTICGTPNYIAP...
.EV....LM.............GKHSGHSFEVDIWSLGVMLYALLI.....GK......P
PFQ.AR........DVNTIYERIKCRDFSFPRDKPIS.......................
..................DEGKILIRDILSLDPIERPS.....LTEIMDYVWF
>RAD53_YEAST/198-466
SIIDEVVGQGAFATV..KKAIERTTGK........TFAVKIISKRKVIGNMDGVTR....
................ELEVLQKL.N...HPRI..VRLKGFYED................
..TESYY..MVMEFVSGG.....DLM..DFVA................AHGAV...GEDA
GREISRQILTAIKYIHS.M..........GISHRDLKPDNILIEQDDPVL..........
........VKITDFGLAKV..................QGNGS.FMKTFCGTLAYVAP...
.EV....IRGKDTSV..SPDEYEERNEYSSLVDMWSMGCLVYVILT.....GH......L
PFS.GS........TQDQLYKQIGRGSYHEGPLKDFRIS.....................
..................EEARDFIDSLLQVDPNNRST.....AAKALNHPWI
>KPK2_PLAFK/111-364
YVLNKKIGKGSFSTA..YIGTNILYGN........RVVVKEVDKSKVKESNVYT......
................EIEVLRKV.M...HKYI..IKLISAYEQ................
..EGFVY..LVLEYLKGG.....ELF..EYLN................NNGPY...TEQV
AKKAMKRVLIALEALHS.N..........GVVHRDLKMENLMLE..NPNDPS........
.......SLKIIDFGLAS...................FLNSP.SMNMRCGSPGYVAP...
.EI....LK...............CASYGTKVDIFSLGVILFNILC.....GY......P
PFR.GN........NVKEIFKKNMRCHISFNTKHWINKS.....................
..................ESVKEIILWMCCKNPDDRCT.....ALQALGHQWF
>K6A1_MOUSE/407-664
YVVKETIGVGSYSVC..KRCVHKATNM........EYAVKVIDKSKRDPSE.........
................EIEILLRYGQ...HPNI..ITLKDVYDD................
..GKHVY..LVTELMRGG.....ELL..DKIL................RQKFF...SERE
ASFVLHTISKTVEYLHS.Q..........GVVHRDLKPSNILYV.DESGNPE........
.......CLRICDFGFAKQL.................RAENG.LLMTPCYTANFVAP...
.EV....LK...............RQGYDEGCDIWSLGILLYTMLA.....GY......T
PFA.NG.....PSDTPEEILTRIGSGKFTLSGGNWNTVS.....................
..................ETAKDLVSKMLHVDPHQRLT.....AKQVLQHPWI
>PHKG2_RAT/24-291
YDPKDIIGRGVSSVV..RRCVHRATGD........EFAVKIMEVSAERLSLEQLEEVRDA
.............TRREMHILRQVAG...HPHI..ITLIDSYES................
..SSFMF..LVFDLMRKG.....ELF..DYLT................EKVAL...SEKE
TRSIMRSLLEAVNFLHV.N..........NIVHRDLKPENILLD.DNMQI..........
.........RLSDFGFSCH..................LEPGE.KLRELCGTPGYLAP...
.EI....LKCS.........MDETHPGYGKEVDLWACGVILFTLLA.....GS......P
PFW.HR........RQILMLRMIMEGQYQFSSPEWDDRS.....................
..................NTVKDLIAKLLQVDPNARLT.....AEQALQHPFF
>KCC4_MOUSE/42-296
FEVESELGRGATSIV..YRCKQKGTQK........PYALKVLKKTVDKKIVRT.......
................EIGVLLRL.S...HPNI..IKLKEIFET................
..PTEIS..LVLELVTGG.....ELF..DRIV................EKGYY...SERD
ARDAVKQILEAVAYLHE.N..........GIVHRDLKPENLLYA..TPAPDA........
.......PLKIADFGLSKI..................VEHQV.LMKTVCGTPGYCAP...
.EI....LR...............GCAYGPEVDMWSVGIITYILLC.....GF......E
PFY.DE.......RGDQFMFRRILNCEYYFISPWWDEVS.....................
..................LNAKDLVKKLIVLDPKKRLT.....TFQALQHPWV
>CDPK_SOYBN/34-292
YEVGRKLGQGQFGTT..FECTRRASGG........KFACKSIPKRKLLCKEDYEDVWR..
................EIQIMHHLSE...HANV..VRIEGTYED................
..STAVH..LVMELCEGG.....ELF..DRIV................QKGHY...SERQ
AARLIKTIVEVVEACHS.L..........GVMHRDLKPENFLFD..TIDEDA........
.......KLKATDFGLSVF..................YKPGE.SFCDVVGSPYYVAP...
.EV....LR................KLYGPESDVWSAGVILYILLS.....GV......P
PFW.AE........SEPGIFRQILLGKLDFHSEPWPSIS.....................
..................DSAKDLIRKMLDQNPKTRLT.....AHEVLRHPWI
>MYLK_CHICK/1453-1708
YNIEERLGSGKFGQV..FRLVEKKTGK........VWAGKFFKAYSAKEKENIRD.....
................EISIMNCL.H...HPKL..VQCVDAFEE................
..KANIV..MVLEMVSGG.....ELF..ERII...............DEDFEL...TERE
CIKYMRQISEGVEYIHK.Q..........GIVHLDLKPENIMCV.NKTGTS.........
........IKLIDFGLARR..................LESAG.SLKVLFGTPEFVAP...
.EV....IN...............YEPIGYETDMWSIGVICYILVS.....GL......S
PFM.GD........NDNETLANVTSATWDFDDEAFDEIS.....................
..................DDAKDFISNLLKKDMKSRLN.....CTQCLQHPWL
>KIN1_SCHPO/125-395
YVLGKTIGAGSMGKV..KVAHHLKTGE........QFAIKIVTRLHPDITKAKAAASAEA
TKAAQSEKNKEIRTVREAALSTLL.R...HPYI..CEARDVYIT................
..NSHYY..MVFEFVDGG.....QML..DYII................SHGKL...KEKQ
ARKFVRQIGSALSYLHQ.N..........SVVHRDLKIENILIS.KTGDI..........
.........KIIDFGLSNL..................YRRQS.RLRTFCGSLYFAAP...
.EL....LN..............AQPYIGPEVDVWSFGIVLYVLVC.....GK......V
PFD.DQ........NMSALHAKIKKGTVEYPSYLS.........................
..................SDCKGLLSRMLVTDPLKRAT.....LEEVLNHPWM
>CDR1_SCHPO/12-258
WRLGKTLGTGSTSCV..RLAKHAKTGD........LAAIKIIPIRYASIGM.........
................EILMMRLL.R...HPNI..LRLYDVWTD................
..HQHMY..LALEYVPDG.....ELF..HYIR................KHGPL...SERE
AAHYLSQILDAVAHCHR.F..........RFRHRDLKLENILIKVNEQQI..........
.........KIADFGMATV..................EPNDS.CLENYCGSLHYLAP...
.EI....VS..............HKPYRGAPADVWSCGVILYSLLS.....NK......L
PFG.GQ........NTDVIYNKIRHGAYDLPSSIS.........................
..................SAAQDLLHRMLDVNPSTRIT.....IPEVFSHPFL
>MEK1_YEAST/162-444
EITNRIVGNGTFGHV..LITHNSKERDEDVCYHPENYAVKIIKLKPNKFDK.........
................EARILLRL.D...HPNI..IKVYHTFCD................
.RNNHLY..IFQDLIPGG.....DLF..SYLA................KGDCLTSMSETE
SLLIVFQILQALNYLHD.Q..........DIVHRDLKLDNILLC..TPEPCT........
.......RIVLADFGIAKDL.................NSNKE.RMHTVVGTPEYCAP...
.EVGFRANRKAYQSF..SRAATLEQRGYDSKCDLWSLGVITHIMLT.....GI......S
PFY.GD.......GSERSIIQNAKIGKLNFKLKQWDIVS.....................
..................DNAKSFVKDLLQTDVVKRLN.....SKQGLKHIWI
>PIM1_HUMAN/38-290
YQVGPLLGSGGFGSV..YSGIRVSDNL........PVAIKHVEKDRISDWGELPNGTRV.
..............PMEVVLLKKVSS..GFSGV..IRLLDWFER................
..PDSFV..LILERPEPVQ....DLF..DFIT................ERGAL...QEEL
ARSFFWQVLEAVRHCHN.C..........GVLHRDIKDENILID.LNRGE..........
........LKLIDFGSGA...................LLKDT.VYTDFDGTRVYSPP...
.EW....IR..............YHRYHGRSAAVWSLGILLYDMVC.....GD......I
PFE.HD.....EEIIRGQVFFRQRVS..................................
..................SECQHLIRWCLALRPSDRPT.....FEEIQNHPWM
>KAB7_YEAST/1096-1354
FVSLQKMGEGAYGKV..NLCIHKKNRY........IVVIKMIFKERILVDTWVRDRKLGT
.............IPSEIQIMATL.NKKPHENI..LRLLDFFED................
..DDYYY....IETPVHGETGCIDLF..DLIE................FKTNM...TEFE
AKLIFKQVVAGIKHLHD.Q..........GIVHRDIKDENVIVD.SKGFV..........
.........KIIDFGSAA...................YVKSG.PFDVFVGTIDYAAP...
.EV....LG..............GNPYEGQPQDIWAIGILLYTVVF.....KE......N
PFY...............NIDEILEGDLKFNNAEEVS.......................
..................EDCIELIKSILNRCVPKRPT.....IDDINNDKWL
>CSK21_CHICK/39-324
YQLVRKLGRGKYSEV..FEAINITNNE........KVVVKILKPVKKKKIKR........
................EIKILENLRG...GPNI..ITLADIVKDP...............
.VSRTPA..LVFEHVNNT.....DFK.....................QLYQTL...TDYD
IRFYMYEILKALDYCHS.M..........GIMHRDVKPHNVMID.HEHRK..........
........LRLIDWGLAEF..................YHPGQ.EYNVRVASRYFKGP...
.EL....LV..............DYQMYDYSLDMWSLGCMLASMIF.....RK......E
PFF.HG....HDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSR.......
..KRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLT.....AREAMEHPYF
>MK04_HUMAN/20-312
FVDFQPLGFGVNGLV..LSAVDSRACR........KVAVKKIALSDARSMKHALR.....
................EIKIIRRL.D...HDNI..VKVYEVLGPKGTDL.......QGEL
FKFSVAY..IVQEYMETDLARLLEQG.........................TL...AEEH
AKLFMYQLLRGLKYIHS.A..........NVLHRDLKPANIFIS.TEDLV..........
........LKIGDFGLARIVD..............QHYSHKG.YLSEGLVTKWYRSP...
.RL....LL..............SPNNYTKAIDMWAAGCILAEMLT.....GR......M
LFA.GA.....HELEQMQLILETIPVIREEDKDELLRVMPSFVSSTWEV...........
......KRPLRKLLPEVNSEAIDFLEKILTFNPMDRLT.....AEMGLQHPYM
>ERK1_CANAL/68-371
YQILEIVGEGAYGIV..CSAIHKPSQQ........KVAIKKIEPFERSMLCLRTLR....
................ELKLLKHF.N...HENI..ISILAIQRPIN.............Y
ESFNEIY..LIQELMETDLHRVIRTQ.........................NL...SDDH
IQYFIYQTLRALKAMHS.A..........NVLHRDLKPSNLLLN.SNCDL..........
.........KICDFGLARSIA..............SQEDNYG.FMTEYVATRWYRAP...
.EI....ML..............TFQEYTTAIDVWSVGCILAEMLS.....GR......P
LFP.GR.....DYHNQLWLIMEVLGTPNMEDYYNIKSKRAREYIRSLPFCKKIPFSELFA
NTNNNTSTSNTGGRTNINPLALDLLEKLLIFNPAKRIT.....VEDALKHPYL
>KKIA_HUMAN/5-288
YEKIGKIGEGSYGVV..FKCRNRDTGQ........IVAIKKFLESEDDPVIKKIALR...
................EIRMLKQL.K...HPNL..VNLLEVFRR................
..KRRLH..LVFEYCDHTVLHELDRY.......................QRGV...PEHL
VKSITWQTLQAVNFCHK.H..........NCIHRDVKPENILIT.KHSVI..........
.........KLCDFGFARLL.................TGPSD.YYTDYVATRWYRSP...
.EL....LV..............GDTQYGPPVDVWAIGCVFAELLS.....GV......P
LWP.GK.....SDVDQLYLIRKTLGDLIPRHQQVFSTNQYFSGVKIPDPE..........
.....DMEPLELKFPNISYPALGLLKGCLHMDPTERLT.....CEQLLHHPYF
>MAK_RAT/4-284
YTTMRQLGDGTYGSV..LMGKSNESGE........LVAIKRMKRKFYSWDECMNLR....
................EVKSLKKL.N...HANV..IKLKEVIRE................
..NDHLY..FIFEYMKENLYQLMKDR.......................NKLF...PESV
IRNIMYQILQGLAFIHK.H..........GFFHRDMKPENLLCM.GPELV..........
.........KIADFGLARE..................LRSQP.PYTDYVSTRWYRAP...
.EV....LL..............RSSVYSSPIDVWAVGSIMAELYT.....FR......P
LFP.GT.....SEVDEIFKICQVLGTPKKSDWPEGYQLASSMNFRFPQCI..........
......PINLKTLIPNASSEAIQLMTEMLNWDPKKRPT.....ASQALKHPYF
>SGV1_YEAST/60-366
YREDEKLGQGTFGEV..YKGIHLETQR........QVAMKKIIVSVEKDLFPITAQR...
................EITILKRL.N...HKNI..IKLIEMVYDHSPDIT.....NAASS
NLHKSFY..MILPYMVADLSGVLHNP.......................RINL...EMCD
IKNMMLQILEGLNYIHC.A..........KFMHRDIKTANILID.HNGVL..........
.........KLADFGLARLYYGCPPN.....LKYPGGAGSGA.KYTSVVVTRWYRAP...
.EL....VL..............GDKQYTTAVDIWGVGCVFAEFFE.....KK......P
ILQ.GK.....TDIDQGHVIFKLLGTPTEEDWAVARYLPGAELTTTNYK...........
......PTLRERFGKYLSETGLDFLGQLLALDPYKRLT.....AMSAKHHPWF
>KIN28_YEAST/7-290
YTKEKKVGEGTYAVV..YLGCQHSTGR........KIAIKEIKTSEFKDGLDMSAIR...
................EVKYLQEM.Q...HPNV..IELIDIFMA................
..YDNLN..LVLEFLPTDLEVVIKDK.......................SILF...TPAD
IKAWMLMTLRGVYHCHR.N..........FILHRDLKPNNLLFS.PDGQI..........
.........KVADFGLARAI.................PAPHE.ILTSNVVTRWYRAP...
.EL....LF..............GAKHYTSAIDIWSVGVIFAELML.....RI......P
YLP.GQ.....NDVDQMEVTFRALGTPTDRDWPEVSSFMTYNKLQIYPPP..........
.....SRDELRKRFIAASEYALDFMCGMLTMNPQKRWT.....AVQCLESDYF
>CDC21_MEDSA/1-284
GENVEKIGEGTYGVV..YKARDRVTNE........TIALKKIRLEQEDEGVPSTAIR...
................EISLLKEM.Q...HRNI..VRLQDVVHS................
..DKRLY..LVFEYLDLDLKKHMDSS.PEFIK........................DPRQ
VKMFLYQMLCGIAYCHS.H..........RVLHRDLKPQNLLIDRRTNSL..........
.........KLADFGLARAF.................GIPVR.TFTHEVVTLWYRAP...
.EI....LL..............GSRHYSTPVDVWSVGCIFAEMAN.....RR......P
LSP.GD.....SEIDELFKIFRILGTPNEDTWPGVTSLPDFKSTFPRWP...........
......SKDLATVVPNLEPAGLDLLNSMLCLDPTKRIT.....ARSAVEHEYF
>CTK1_YEAST/183-469
YLRIMQVGEGTYGKV..YKAKNTNTEK........LVALKKLRLQGEREGFPITSIR...
................EIKLLQSF.D...HPNV..STIKEIMVE................
.SQKTVY..MIFEYADNDLSGLLLNK.......................EVQI...SHSQ
CKHLFKQLLLGMEYLHD.N..........KILHRDVKGSNILID.NQGNL..........
.........KITDFGLARK..................MNSRA.DYTNRVITLWYRPP...
.EL....LL..............GTTNYGTEVDMWGCGCLLVELFN.....KT......A
IFQ.GS.....NELEQIESIFKIMGTPTINSWPTLYDMPWFFMIMPQQTTKY........
....VNNFSEKFKSVLPSSKCLQLAINLLCYDQTKRFS.....ATEALQSDYF
>GSK3A_RAT/119-403
YTDIKVIGNGSFGVV..YQARLAETRE........LVAIKKVLQDKRFKNR.........
................ELQIMRKL.D...HCNI..VRLRYFFYSSG..............
EKKDELYLNLVLEYVPETVYRVARHF....................TKAKLII...PIIY
VKVYMYQLFRSLAYIHS.Q..........GVCHRDIKPQNLLVD.PDTAV..........
........LKLCDFGSAKQ..................LVRGE.PNVSYICSRYYRAP...
.EL....IF..............GATDYTSSIDVWSAGCVLAELLL.....GQ......P
IFP.GD.....SGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKA...........
......HPWTKVFKSRTPPEAIALCSSLLEYTPSSRLS.....PLEACAHSFF
>KPRO_MAIZE/534-812
RKFKVELGRGESGTV..YKGVLEDDRH.........VAVKKLENVRQGKEVFQA......
................ELSVIGRI.N...HMNL..VRIWGFCSE................
..GSHRL..LVSEYVENG.....SLA..NILF................SEGGNILLDWEG
RFNIALGVAKGLAYLHH.EC.......LEWVIHCDVKPENILLD.QAFEP..........
.........KITDFGLVKLLN...............RGGSTQ.NVSHVRGTLGYIAP...
.EW....VS...............SLPITAKVDVYSYGVVLLELLT.....G.......T
RVS.ELVGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLDSKLN...............
..........RPVNYVQARTLIKLAVSCLEEDRSKRPT.....MEHAVQT..L
>PHY1_CERPU/1004-1282
IQITGSLGSGSSATV..EKAVWLGTP..........VAKKTFYGRNNEDFKR........
................EVEILAEL.C...HPNI..TSMFCSPLY................
..RRKCS..IIMELMDG......DLL..ALMQ.......RRLDRNEDHDSPPF...SILE
VVDIILQTSEGMNYLHE.K..........GIIHRDLKSMNILVK.SVKVTKSEI......
....GYVHVKVADFGLSKTKD...............SSTRYS.NQTWNRGTNRWMAP...
.EV....INLGYESTEGEISFDGKVPKYPLKSDVYSFGMVCYEVLT.....GD......V
PFPEEK.....NPNNVKRMVLEGVRPDLPAHCP...........................
..................IELKALITDCWNQDPLKRPS.....FAVICQK..L
>M3K9_HUMAN/3-262
LTLEEIIGIGGFGKV..YRAFWIGDE..........VAVKAARHDPDEDISQTIENVR..
...............QEAKLFAML.K...HPNI..IALRGVCLK................
..EPNLC..LVMEFARGG.....PLN..RVLS.................GKRI...PPDI
LVNWAVQIARGMNYLHDEAI........VPIIHRDLKSSNILIL.QKVENGDLS......
.....NKILKITDFGLAR...................EWHRT.TKMSAAGTYAWMAP...
.EV....IR...............ASMFSKGSDVWSYGVLLWELLT.....GE......V
PFR.GI....DGLRVAYGVAMNKLALPIPSTCP...........................
..................EPFAKLMEDCWNPDPHSRPS.....FTNILDQ..L
>MIL_AVIMH/82-339
VLLSTRIGSGSFGTV..YKGKWHGD...........VAVKILKVVDPTPEQFQAFRN...
................EVAVLRKT.R...HVNI..LLFMGYMT.................
..KDNLA..IVTQWCEGS.....SLY..KHLH...............VQETKF...QMFQ
LIDIARQTAQGMDYLHA.K..........NIIHRDMKSNNIFLH.GGLTV..........
.........KIGDFGLATVKS...............RWSGSQ.QVEQPTGSILWMAP...
.EV....IRM............QDSNPFSFQSDVYSYGIVLYELMT.....GE......L
PYS.HI.....NNRDQIIFMVGRGYASPDLSKLYKNCP......................
..................KAMKRLVADCLKKVREERPL.....FPQILSS..I
>ACVR1_HUMAN/208-495
ITLLECVGKGRYGEV..WRGSWQGEN..........VAVKIFSSRDEKSWFRET......
................ELYNTVML.R...HENI..LGFIASDMTSR..............
HSSTQLW..LITHYHEMG.....SLY..DYLQ.................LTTL...DTVS
CLRIVLSIASGLAHLHI.EIFGT..QGKPAIAHRDLKSKNILVK.KNGQC..........
.........CIADLGLAVMHSQ.............STNQLDV.GNNPRVGTKRYMAP...
.EVLDETIQ.............VDCFDSYKRVDIWAFGLVLWEVARR.MVSNGIVEDYKP
PFY.DVVPNDPSFEDMRKVVCVDQQRPNIPNRWFSDPTL.....................
..................TSLAKLMKECWYQNPSARLT.....ALRIKKT..L
>ACVR2_HUMAN/192-479
LQLLEVKARGRFGCV..WKAQLLNEY..........VAVKIFPIQDKQSWQNEY......
................EVYSLPGM.K...HENI..LQFIGAEKRGT..............
SVDVDLW..LITAFHEKG.....SLS..DFLK.................ANVV...SWNE
LCHIAETMARGLAYLHE.DIPGLKDGHKPAISHRDIKSKNVLLK.NNLTA..........
.........CIADFGLALKFE...............AGKSAG.DTHGQVGTRRYMAP...
.EVLEGAIN..............FQRDAFLRIDMYAMGLVLWELASRCTAADGPVDEYML
PFE.EEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGM.....................
..................AMLCETIEECWDHDAEARLS.....AGCVGER..I
>CDC15_YEAST/25-272
YHLKQVIGRGSYGVV..YKAINKHTDQ........VVAIKEVVYENDEELNDIMA.....
................EISLLKNL.N...HNNI..VKYHGFIRK................
..SYELY..ILLEYCANG.....SLR..RLIS...............RSSTGL...SENE
SKTYVTQTLLGLKYLHG.E..........GVIHRDIKAANILLS.ADNTV..........
.........KLADFGVS....................TIVNS.SALTLAGTLNWMAP...
.EI....LG...............NRGASTLSDIWSLGATVVEMLT.....KN......P
PYH.NL.....TDANIYYAVENDTYYPPSSFS............................
..................EPLKDFLSKCFVKNMYKRPT.....ADQLLKHVWI
>BYR2_SCHPO/394-658
WIRGALIGSGSFGQV..YLGMNASSGE........LMAVKQVILDSVSESKDRHAKLLDA
.............LAGEIALLQEL.S...HEHI..VQYLGSNLN................
..SDHLN..IFLEYVPGG.....SVA..GLLT................MYGSF...EETL
VKNFIKQTLKGLEYLHS.R..........GIVHRDIKGANILVD.NKGKI..........
.........KISDFGISKKLELN...........STSTKTGG.ARPSFQGSSFWMAP...
.EV....VK...............QTMHTEKTDIWSLGCLVIEMLT.....SK......H
PYP.NC.....DQMQAIFRIGENILPEFPSNIS...........................
..................SSAIDFLEKTFAIDCNLRPT.....ASELLSHPFV
>STE20_YEAST/620-871
YANLVKIGQGASGGV..YTAYEIGTNV........SVAIKQMNLEKQPKKELIIN.....
................EILVMKGS.K...HPNI..VNFIDSYVL................
..KGDLW..VIMEYMEGG.....SLT..DVVT.................HCIL...TEGQ
IGAVCRETLSGLEFLHS.K..........GVLHRDIKSDNILLS.MEGDI..........
.........KLTDFGFCAQI.................NELNL.KRTTMVGTPYWMAP...
.EV....VS...............RKEYGPKVDIWSLGIMIIEMIE.....GE......P
PYL.NE.....TPLRALYLIATNGTPKLKEPENLS.........................
..................SSLKKFLDWCLCVEPEDRAS.....ATELLHDEYI
>MKK1_YEAST/221-488
IETLGILGEGAGGSV..SKCKLKNGSK........IFALKVINTLNTDPEYQKQIFR...
................ELQFNRSF.Q...SEYI..VRYYGMFTDD...............
.ENSSIY..IAMEYMGGR.....SLD..............AIYKNLLERGGRI...SEKV
LGKIAEAVLRGLSYLHE.K..........KVIHRDIKPQNILLN.ENGQV..........
.........KLCDFGVSG...................EAVNS.LATTFTGTSFYMAP...
.ER....IQ...............GQPYSVTSDVWSLGLTILEVAN.....GK......F
PCS.SE.....KMAANIAPFELLMWILTFTPELKDEPESNI...................
...............IWSPSFKSFIDYCLKKDSRERPS.....PRQMINHPWI
>STE7_YEAST/191-466
LVQLGKIGAGNSGTV..VKALHVPDSK........IVAKKTIPVEQNNSTIINQLVR...
................ELSIVKNVKP...HENI..ITFYGAYYNQ...............
HINNEII..ILMEYSDCG.....SLD..KILSVY...KRFVQRGTVSSKKTWF...NELT
ISKIAYGVLNGLDHLYRQY..........KIIHRDIKPSNVLIN.SKGQI..........
.........KLCDFGVSK...................KLINS.IADTFVGTSTYMSP...
.ER....IQ...............GNVYSIKGDVWSLGLMIIELVT.....GE......F
PLG.GHNDTPDGILDLLQRIVNEPSPRLPKDRIYS.........................
..................KEMTDFVNRCCIKNERERSS.....IHELLHHDLI
>BYR1_SCHPO/66-320
LEVVRHLGEGNGGAV..SLVKHRNI...........FMARKTVYVGSDSKLQKQILR...
................ELGVLHHC.R...SPYI..VGFYGAFQY................
..KNNIS..LCMEYMDCG.....SLD..AILR................EGGPI...PLDI
LGKIINSMVKGLIYLYNVL..........HIIHRDLKPSNVVVN.SRGEI..........
.........KLCDFGVSG...................ELVNS.VAQTFVGTSTYMSP...
.ER....IR...............GGKYTVKSDIWSLGISIIELAT.....QE......L
PWSFSNIDDSIGILDLLHCIVQEEPPRLPSSFP...........................
..................EDLRLFVDACLHKDPTLRAS.....PQQLCAMPYF
>KMOS_CERAE/60-338
VCLLQRLGAGGFGSV..YKATYHGVP..........VAIKQVNKCTKNRLASRRSFWA..
................ELNVARLR.....HDNI..VRVVAASTRT...............
PAGSNSLGTIIMEFGGNV.....TLH..QVIYGAASHPEGDAGEPHCSTGGPL...TLGK
CLKYSLDVVNGLLFLHS.Q..........SIVHLDLKPANILIS.EQDVC..........
.........KISDFGCSEKLE..............DLLCFQT.PLYPLGGTYTHRAP...
.EL....LK...............GEGVTPKADIYSFAITLWQMTT.....KQ......A
PYS.GE.....RQHILYAVVAYDLRPSLSAAVFQDSLPG.....................
..................QRLGDVIRRCWRPSAAQRPS.....ARPLLVD..L
>PKN1_MYXXA/59-320
FRLVRRLGRGGMGAV..YLGEHVSIGS........RVAVKVLHAHLTMYPELVQRFHA..
................EARAVNLI.G...HENI..VSIFDMDAT................
..PPRPY..LIMEFLDGA.....PLS....................AWVGTPL...AAGA
VVSVLSQVCDALQAAHA.R..........GIVHRDLKPDNIFLV.RRNGNAP........
.......FVKVLDFGIAKLAD...............AHMPQT.HAGIIVGTPEYMAP...
.EQ....SL...............GRGVDGRADLYALGVIAYQLLT.....GR......L
PFN.DE.....GLAAQLVAHQLRPPPPPSSVYPAVS........................
..................AALEHVILRALAKKPEDRYA....SIAAFRNALQV
>KKL6_YEAST/192-508
WKKVRPIGSGNFSTVLLYELMDQSNPKL......KQVAVKRLKYPEELSNVEQINTSLRY
KETLS...RLENSLTRELQVLKSL.N...HPCI..VKLLGIN.NPIFVTSKKPLCDLIIK
TPRALPPCDMIMSYCPAG.....DLL..AAVM...............ARNGRL...EAWL
IQRIFTEVVLAVKYLHE.N..........SIIHRDLKLENILLK...YSFDDINSFRDS.
PIYCKQNFIELADFGLCKK..................IENNE.MCTARCGSEDYVSP...
.EI....LM..............GVPYDGHLSDTWALGVILYSLFE.....DR......L
PFD.PP.....PNASARQRSRATSHRIARFDWRWYRLSDY....................
................KTNVGKQIVENTLTRKNQRWS......INEIYESPFV
>NPR1_YEAST/438-742
IKTGADLGAGAGGSV..KLAQRISDNK........IFAVKEFRTKFENESKRDYVKKI..
..............TSEYCIGTTL.N...HPNI..IETIEIVYE................
..NDRIL..QVMEYCEY......DLF..AIVM.................SNKM...SYEE
ICCCFKQILTGVQYLHS.I..........GLAHRDLKLDNCVIN.EKGIV..........
.........KLIDFGAAVVFSY.............PFSKNLV.EASGIVGSDPYLAP...
.EV....CI..............FAKYDPRPVDIWSSAIIFACMIL.....KK......F
PWKIPK.....LRDNSFKLFCSGRDCDSLSSLVTRTPDPPSYDESHSTEKKKPESSSNNV
SDPNNVNIGPQRLLHSLPEETQHIVGRMIDLAPACRGN.....IEEIMEDPWI
>SAT4_YEAST/316-590
GRCQEVLGKGAFGVV..RICQKKNVSSQDGNKSEKLYAVKEFKRRTSESAEKYSKRLT..
...............SEFCISSSL.H...HTNI..VTTLDLFQD................
.AKGEYC..EVMEYCAGG.....DLF..TLVV................AAGKL...EYME
ADCFFKQLIRGVVYMHE.M..........GVCHRDLKPENLLLT.HDGVL..........
.........KITDFGNSECFKM.............AWEKNIH.LSGGVCGSSPYIAP...
.EE....YI..............KEEFDPRPVDIWACGVIYMAMRT.....GR......Q
LWS.SA.....EKDDPFYMNYLKGRKEKGGYEPIESLKR.....................
..................ARCRNVIYSMLDPVPYRRIN.....GKQILNSEWG
>RAN1_SCHPO/18-295
LRFVSIIGAGAYGVV..YKAEDIYDGT........LYAVKALCKDGLNEKQKKLQAR...
................ELALHARVSS...HPYI..ITLHRVLET................
..EDAIY..VVLQYCPNG.....DLF..TYIT.................EKKVYQGNSHL
IKTVFLQLISAVEHCHS.V..........GIYHRDLKPENIMVG.NDVNT..........
........VYLADFGLA....................TTEPY.SSDFGCGSLFYMSPECQ
REVKKLSSLSDMLPVTPEPIESQSSSFATAPNDVWALGIILINLCC.....KR......N
PWK.RACSQTDGTYRSYVHNPSTLLSILPIS.............................
..................RELNSLLNRIFDRNPKTRIT.....LPELSTL..V
>KR1_PRVKA/53-332
FEVLQPLQSGSEGRV..FVARRPGEAD........TVVLKVGQKPSTLM...........
................EGMLLQRL.S...HDNV..MRMKQMLAR................
..GPATC..LVLPHFRC......DLY..SYLT...............MRDGPL...DMRD
AGCVIRAVLRGLAYLHG.M..........RIMHRDVKAENIFLE.DVDTV..........
.........CLGDLGAARC..................NVAAP.NFYGLAGTIETNAP...
.EV....LA...............RDRYDTKVDVWGAGVVLFETLA.............Y
PKT.ITGGDEPAINGEMHLIDLIRALGVHPEEFPPDTRLRSEFVRYAGTHRQ........
....PYTQYARVARLGLPETGAFLIYKMLTFDPVRRPS.....ADEILNFGMW
>KR1_HHV11/191-478
FTIHGALTPGSEGCV..FDSSHPDYPQ........RVIVKAGWYTSTSH...........
................EARLLRRL.D...HPAI..LPLLDLHVV................
..SGVTC..LVLPKYQA......DLY..TYLS...............RRLNPL...GRPQ
IAAVSRQLLSAVDYIHR.Q..........GIIHRDIKTENIFIN.TPEDI..........
.........CLGDFGAACFVQ...............GSRSSP.FPYGIAGTIDTNAP...
.EV....LA...............GDPYTTTVDIWSAGLVIFETAV.....HN......A
SLF.SAPRGPKRGPCDSQITRIIRQAQVHVDEFSPHPESRLTSRYRSRAAGNN.......
..RPPYTRPAWTRYYKMDIDVEYLVCKALTFDGALRPS.....AAELLCLPLF
>WEE1_HUMAN/299-569
FHELEKIGSGEFGSV..FKCVKRLDGC........IYAIKRSKKPLAGSVDEQNALR...
................EVYAHAVLGQ...HSHV..VRYFSAWAE................
..DDHML..IQNEYCNGG.....SLA..DAIS...............ENYRIMSYFKEAE
LKDLLLQVGRGLRYIHS.M..........SLVHMDIKPSNIFIS.RTSIPNAASEEGDED
DWASNKVMFKIGDLGH.....................VTRIS.SPQVEEGDSRFLAN...
.EV....LQ..............ENYTHLPKADIFALALTVVCAAG.....AE......P
LPR.NGDQWHEIRQGRLPRIPQVLS...................................
..................QEFTELLKVMIHPDPERRPS.....AMALVKHSVL
>HRR25_YEAST/9-273
FRIGRKIGSGSFGDI..YHGTNLISGE........EVAIKLESIRSRHPQLDY.......
................ESRVYRYL.S...GGVG..IPFIRWFGR................
.EGEYNA..MVIDLLGPSLEDLFNYC.......................HRRF...SFKT
VIMLALQMFCRIQYIHG.R..........SFIHRDIKPDNFLMG..VGRRGS........
.......TVHVIDFGLSKKYRDF..........NTHRHIPYR.ENKSLTGTARYASV...
.NT....HL...............GIEQSRRDDLESLGYVLIYFCK.....GS......L
PWQ.GL.....KATTKKQKYDRIMEKKLNVSVETLCSGL.....................
.................PLEFQEYMAYCKNLKFDEKPD.......YLFLARLF